Medications For Anxiety Disorder and Depression Many people use medication to manage anxiety, but they're not the only option. Psychotherapy and exercise can be powerful treatments too. Certain antidepressants, such as SSRIs (citalopram, Lexapro, fluoxetine, Prozac, paroxetine, Zoloft) also help with anxiety. Others, like histamine blockers such Vistaril (hydroxyzine) can
